Jardiance for Heart Failure: Benefits and Side Effects

Heart failure affects more than 6.7 million adults in the United States, creating a significant burden on both patients and the healthcare system. For decades, heart failure has been difficult to manage, but a breakthrough treatment, Jardiance for Heart Failure (empagliflozin), offers new hope. The drug, originally developed for diabetes, received FDA approval to reduce cardiovascular deaths and hospitalizations in patients with heart failure.

This guide explains how Jardiance works for heart failure, its benefits, clinical evidence, safety considerations, and how it can help improve the quality of life for heart failure patients.

Important points

• Jardiance is approved by the FDA to reduce the risk of cardiovascular death and hospitalization in heart failure patients.

• It benefits both diabetics and non-diabetics as the ejection fraction is lowered or maintained.

• Jardiance improves heart function, reduces fluid accumulation, and protects kidney health.

What is Jardiance?

Jardiance, also known as empagliflozin, is a prescription drug recommended by doctors to manage type 2 diabetes. It helps maintain blood sugar levels by stopping the kidneys from reabsorbing glucose and allowing additional sugar to be excreted through urine. But now that it has FDA approval, health care providers are beginning to prescribe it to lower the risk of heart failure. Helps prevent heart failure by reducing fluid and sodium accumulation in blood vessels. Learn more about Jardiance’s role in heart failure.

Jardiance’s role in heart failure

Jardiance (empagliflozin) is a prescription drug that belongs to a group of drugs called “sodium-glucose cotransporter 2 (SGLT2) inhibitors.” It was originally approved for type 2 diabetes in 2014, but its effectiveness has improved significantly in recent years. In 2021, focus will be on heart failure treatment. US FDA has approved 10 mg of Jardiance to reduce the risk of cardiovascular death and hospitalization in adults with heart failure and reduced ejection fraction (decreased ability of the heart to pump blood).

Here’s how Jardiance plays an important role in heart failure treatment:

It improves the symptoms of heart failure and helps reduce the number of hospital visits.

Improves the ability of the heart to pump blood efficiently in patients with heart failure.

It reduces the amount of salt and sugar in the blood that the kidneys need to filter, thus protecting kidney health.

Treats heart-related problems in heart failure patients and lowers the risk of death.

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  improves vascular function

Improves the ability of blood vessels to dilate, supporting better blood circulation.

Reduces the risk of oxidative stress and inflammation, which play a major role in the progression of heart failure.

Clinical evidence supporting stigma against heart failure treatment

According to the American College of Cardiology, The EMPEROR-Reduced trial showed that Jardiance was highly potent in improving heart failure outcomes in patients with reduced ejection fraction. Studies have shown that heart failure patients who use Jardiance experience the following symptoms:

• a 29% 25% reduced risk of cardiovascular death or hospitalization compared to those taking a placebo.

• The chance of heart failure progression is lowered and the quality of life is improved.

moreover, EMPEROR-Preserved trial Also, affirmation that it reduces the risk of hospitalization or cardiovascular death in heart failure patients whose ejection fraction (the heart normally pumps blood, but is very stiff to fill it properly) is preserved. The results were also demonstrated. All these findings indicate that Jardiance may be beneficial in both categories of heart failure.

How does Jardiance work in heart failure?

Here’s how Jardiance treats heart failure.

It blocks the activity of the SGLT2 protein present in the kidneys, reducing glucose reabsorption and supporting glucose excretion through urine.

It promotes the excretion of excess water and sodium, reducing the risk of swelling and fluid accumulation within the heart.

It reduces pressure on the heart and increases its ability to pump or pump blood efficiently.

Reduces oxidative stress and inflammation that can cause heart damage.

Lower blood pressure levels further reduce the strain on your heart.

Protects kidney function by controlling blood sugar levels and reducing fluid overload.

The combined effect of all these strengthens heart function and reduces symptoms of heart failure.

Jardiance safety information

When to avoid Jardiance:

Jardiance may not be suitable in the following cases:

• severe renal impairment

• acute heart failure

• polycystic kidney disease

• pregnant or breastfeeding

• Severe hypotension (hypotension)

• Allergic reaction to Jardiance

• active bladder cancer

potential side effects

Common side effects:

• Dehydration or excessive thirst.

• Urinary tract infection or genital yeast infection.

Serious side effects:

• Severe dehydration or dizziness.

• Rare cases of diabetic ketoacidosis or Fournier’s gangrene (serious genital infection).

Other possible side effects:

• high blood potassium

• nausea

• fatigue

Important notes: If you experience any unusual symptoms, contact your doctor immediately.

How to get Jardiance?

• Dosage: The recommended starting dose for Jardiance is 10 mg per day. Depending on individual tolerance, the dose can be increased up to 25 mg per day.

• Time: Take at the same time each day in the morning, with or without food.

• Swallowing whole: Do not chew or crush the tablet. Swallow it whole.

• If you miss a dose: If you miss a dose, take it as soon as you remember. Do not use two doses at the same time due to the risk of overdose.

• Stay hydrated: Drink plenty of water and fluids to avoid the risk of dehydration, especially if you are using diuretics or in hot weather.

In case of overdose:

• phone 911emergency services number in case of serious symptoms.

• contact 800-222-1222the poison center service number for overdose emergencies.

Important notes: Always follow your doctor’s instructions regarding dosage and timing.

How to know if Jardiance is working

Look for signs of improvement, such as:

Symptom relief:

Increased activity level:

Reduced number of hospital visits:

Better blood test results:

Note: Always track your symptoms and schedule regular check-ups with your health care provider.

Jardiance drug interactions

If you are receiving Jardiance treatment, be sure to discuss any other medical conditions and current medications with your health care provider. This can prevent the risk of drug interactions and reduce further complications. Jardiance may affect the following drugs:

• Diuretics: May lower blood pressure and worsen dehydration.

• Blood pressure medications: May increase risk of low blood pressure.

• Insulin or diabetes medications: May contribute to lower blood sugar levels.

• RAAS inhibitors: Can cause kidney-related problems.

• NSAIDs: May increase risk of kidney damage, especially from dehydration.

• Lithium: Lithium levels can increase and toxicity can occur.

Does Jardiance only help treat heart failure in people with type 2 diabetes?

No, it’s not. the study Jardiance reports that it may help treat heart failure, whether you have diabetes or not. Patients experienced the same results with drug use, regardless of their type of diabetes. Therefore, the FDA has approved it for heart failure patients with reduced ejection fraction, with or without diabetes.

final thoughts

Jardiance for the treatment of heart failure has been approved by the FDA to reduce the risk of death and hospitalization from cardiovascular disease, and has actually become very popular in recent years. This promotes heart and kidney health. However, it also comes with side effects and should be used with caution as it may lead to further complications. Therefore, it is important for patients considering Jardiance to properly discuss all possible benefits and risks with their doctor.

If you or someone you know suffers from heart failure, talk to your healthcare provider about how Jardiance can help improve your heart health and overall quality of life.

Please also read How to buy Jardiance online from Canada safely and conveniently

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