The goal is to discuss a new approach method (NAM) for evaluating skin sensitizers.
Key international stakeholders and leading experts from government and industry discuss the current state of science and future areas of research, allowing risk assessors to assess safety based on adequate potency of skin sensitizers within the regulatory framework. to set appropriate usage limits.
The presentation will be by Dr. Anne-Marie Api, RIFM, who will discuss the latest science (NAM and NGRA) for assessing skin sensitization potential of novel chemicals under TSCA (RIFM approach). Dr. Shashi Donsamsetti, IFF, discusses the proposed NGRA framework to address skin sensitization. Dr. Andy Forreryd presents the Senzagen NAMS-GARDskin Dose Response Assay and his GARDskin Potency Assay. EPA’s Dr. Anna Lowitt will present an approach to assessing the potential skin sensitization potential of chemicals, including fragrance substances, based on the TSCA – EPA approach. Inotiv’s Dr. Emily Reinke will talk about Artificial Neural Networks, Support Vector Machine Models, Bayesian Networks, and Decision Her Trees. Dr. Vanessa Rochat, Givaudan, presented an integrated risk-potency-based skin sensitization assessment combining the OECD method, a kinetic peptide reactivity and a “2 out of 3” defined approach, and a risk assessment. Let’s discuss the derivation of the starting point. Evaluation; Dr. Matthias Vey of IFRA will lecture on the risk management paradigm of IFRA standards, including IDEA’s research program built in collaboration with the EU Commission.
The registration fee for FSAC members is $95 and $195 for non-members.go here Register for the workshop.